DIFLUCAN vs MONISTAT 7

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Attribute	DIFLUCAN	MONISTAT 7
Rating	60/100	70/100
Pharmacy pays	$0.42 /mL	—
Type	RX	OTC
Active ingredient	FLUCONAZOLE	MICONAZOLE NITRATE
Manufacturer	Pfizer	Medtech Products
Dosage forms	Powder	Suppository, Topical
Drug class	Azole Antifungal	Azole Antifungal
Boxed warning	None	None
Half-life	about 30 hours (range 20 to 50 hours)	—
Treats	Blastomycosis, Chronic Mucocutaneous Candidiasis, Oral Candidiasis	Aspergillosis, Cutaneous Candidiasis, Vulvovaginal Candidiasis

diflucan monistat 7

Rating

60/100

70/100

Pharmacy pays

$0.42 /mL

—

Type

OTC

Active ingredient

FLUCONAZOLE

MICONAZOLE NITRATE

Manufacturer

Pfizer

Medtech Products

Dosage forms

Powder

Suppository, Topical

Drug class

Azole Antifungal

Boxed warning

None

Half-life

about 30 hours (range 20 to 50 hours)

—

Treats

Blastomycosis, Chronic Mucocutaneous Candidiasis, Oral Candidiasis

Aspergillosis, Cutaneous Candidiasis, Vulvovaginal Candidiasis

Get monistat 7higher-rated option

Advertising disclosure: Some links are affiliate links. We may earn a commission at no extra cost to you. This never affects our independent ratings.

Get treatment online

Licensed online providers — consult & get prescribed if eligible.

SesameCompare online visit prices

Where to buy

Buy over-the-counter from trusted retailers.

AmazonCheck price on Amazon

Frequently asked questions

Which is better-rated, Diflucan or Monistat 7?

By our independent rating, Monistat 7 scores higher — 3.5 vs 3.0 out of 5 for Diflucan. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Diflucan and Monistat 7?

Diflucan contains Fluconazole, while Monistat 7 contains Miconazole Nitrate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.