DIFLUCAN vs FLUCONAZOLE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Attribute	DIFLUCAN	FLUCONAZOLE
Rating	60/100	New
Pharmacy pays	$0.42 /mL	$0.42 /mL
Type	RX	RX
Active ingredient	FLUCONAZOLE	FLUCONAZOLE
Manufacturer	Pfizer	Ivax Sub Teva Pharms
Dosage forms	Powder	Tablet
Drug class	Azole Antifungal	Azole Antifungal
Boxed warning	None	None
Half-life	about 30 hours (range 20 to 50 hours)	about 30 hours (range 20 to 50 hours)
Treats	Blastomycosis, Chronic Mucocutaneous Candidiasis, Oral Candidiasis	Blastomycosis, Chronic Mucocutaneous Candidiasis, Oral Candidiasis

diflucan fluconazole

Rating

60/100

New

Pharmacy pays

$0.42 /mL

Type

Active ingredient

FLUCONAZOLE

Manufacturer

Pfizer

Ivax Sub Teva Pharms

Dosage forms

Powder

Tablet

Drug class

Azole Antifungal

Boxed warning

None

Half-life

about 30 hours (range 20 to 50 hours)

Treats

Blastomycosis, Chronic Mucocutaneous Candidiasis, Oral Candidiasis

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Frequently asked questions

Which is cheaper, Diflucan or Fluconazole?

Pharmacies pay about the same to acquire either one — roughly $0.42 per ml, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Diflucan and Fluconazole?

Both Diflucan and Fluconazole share the active ingredient Fluconazole.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.