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DIFLUCAN IN DEXTROSE 5% IN PLASTIC CONTAINER vs TOLSURA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 17, 2026·How we rate

Possible drug interaction. DIFLUCAN IN DEXTROSE 5% IN PLASTIC CONTAINER and TOLSURA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

64/100
70/100

Pharmacy pays

$0.42 /mL
$0.84 /mL

Type

RX
RX

Active ingredient

FLUCONAZOLE
ITRACONAZOLE

Manufacturer

Dosage forms

Injectable
Capsule

Drug class

Azole Antifungal
Azole Antifungal

Boxed warning

Half-life

about 30 hours (range 20 to 50 hours)
Terminal (elimination) half-life is about 16 to 28 hours after a single dose, rising to roughly 34 to 42 hours with repeated (steady-state) dosing.

Treats

Blastomycosis, Chronic Mucocutaneous Candidiasis, Oral Candidiasis
Aspergillosis, Blastomycosis, Chronic Mucocutaneous Candidiasis

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Frequently asked questions

Which is better-rated, Diflucan in Dextrose 5% in Plastic Container or Tolsura?

By our independent rating, Tolsura scores higher — 3.5 vs 3.2 out of 5 for Diflucan in Dextrose 5% in Plastic Container. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Diflucan in Dextrose 5% in Plastic Container or Tolsura?

Diflucan in Dextrose 5% in Plastic Container costs pharmacies less to acquire — about $0.42 vs $0.84 per ml, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Diflucan in Dextrose 5% in Plastic Container and Tolsura?

Diflucan in Dextrose 5% in Plastic Container contains Fluconazole, while Tolsura contains Itraconazole — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.