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DIFICID vs FLAVORED COLESTID

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 15, 2026·How we rate

Possible drug interaction. DIFICID and FLAVORED COLESTID are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

72/100
64/100

Pharmacy pays

~$4759.74 /30
~$20.09 /30

Type

RX
RX

Active ingredient

FIDAXOMICIN
COLESTIPOL HYDROCHLORIDE

Dosage forms

Powder
Powder

Drug class

Macrolide Antibacterial
Bile Acid Sequestrant

Boxed warning

None
None

Treats

Pseudomembranous Enterocolitis
Coronary Artery Disease, Diarrhea, Pseudomembranous Enterocolitis

Frequently asked questions

Which is better-rated, Dificid or Flavored Colestid?

By our independent rating, Dificid scores higher — 3.6 vs 3.2 out of 5 for Flavored Colestid. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Dificid or Flavored Colestid?

Flavored Colestid costs pharmacies less to acquire — about $20.09 vs $4759.74 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Dificid and Flavored Colestid?

Dificid contains Fidaxomicin, while Flavored Colestid contains Colestipol Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.