DIETHYLPROPION HYDROCHLORIDE vs PLEGINE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 15, 2026·How we rate

Possible drug interaction. DIETHYLPROPION HYDROCHLORIDE and PLEGINE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	DIETHYLPROPION HYDROCHLORIDE	PLEGINE
Rating	70/100	New
Pharmacy pays	~$7.96 /30	~$3.86 /30
Type	RX	RX
Active ingredient	DIETHYLPROPION HYDROCHLORIDE	PHENDIMETRAZINE TARTRATE
Manufacturer	Epic Pharma LLC	Wyeth Ayerst
Dosage forms	Tablet	Tablet
Drug class	Sympathomimetic Amine Anorectic	Sympathomimetic Amine Anorectic
Boxed warning	None	None
Treats	Obesity	Obesity

diethylpropion hydrochloride plegine

Rating

70/100

New

Pharmacy pays

~$7.96 /30

~$3.86 /30

Type

Active ingredient

DIETHYLPROPION HYDROCHLORIDE

PHENDIMETRAZINE TARTRATE

Manufacturer

Epic Pharma LLC

Wyeth Ayerst

Dosage forms

Tablet

Drug class

Sympathomimetic Amine Anorectic

Boxed warning

None

Treats

Obesity

Frequently asked questions

Which is cheaper, Diethylpropion Hydrochloride or Plegine?

Plegine costs pharmacies less to acquire — about $3.86 vs $7.96 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Diethylpropion Hydrochloride and Plegine?

Diethylpropion Hydrochloride contains Diethylpropion Hydrochloride, while Plegine contains Phendimetrazine Tartrate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.