DICLOFENAC SODIUM vs XIFYRM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. DICLOFENAC SODIUM and XIFYRM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	DICLOFENAC SODIUM	XIFYRM
Rating	70/100	70/100
Pharmacy pays	$0.36 /mL	~$0.56 /30
Type	RX	RX
Active ingredient	DICLOFENAC SODIUM	MELOXICAM
Manufacturer	Amneal	Azurity
Dosage forms	Solution, Drops, Topical, Tablet, delayed release, Tablet, extended release, Tablet, Kit	Injectable
Drug class	Nonsteroidal Anti-Inflammatory Drug	Nonsteroidal Anti-Inflammatory Drug
Boxed warning	Boxed warning	Boxed warning
Half-life	about 2 hours (terminal/elimination half-life; the label's table gives a mean of 2.3 hours in healthy adults, with wide variation between people — 48% coefficient of variation)	about 15 to 20 hours
Treats	Juvenile Arthritis, Rheumatoid Arthritis, Dysmenorrhea	Rheumatoid Arthritis, Osteoarthritis

diclofenac sodium xifyrm

Rating

70/100

Pharmacy pays

$0.36 /mL

~$0.56 /30

Type

Active ingredient

DICLOFENAC SODIUM

MELOXICAM

Manufacturer

Amneal

Azurity

Dosage forms

Solution, Drops, Topical, Tablet, delayed release, Tablet, extended release, Tablet, Kit

Injectable

Drug class

Nonsteroidal Anti-Inflammatory Drug

Boxed warning

Half-life

about 2 hours (terminal/elimination half-life; the label's table gives a mean of 2.3 hours in healthy adults, with wide variation between people — 48% coefficient of variation)

about 15 to 20 hours

Treats

Juvenile Arthritis, Rheumatoid Arthritis, Dysmenorrhea

Rheumatoid Arthritis, Osteoarthritis

Frequently asked questions

Which is better-rated, Diclofenac Sodium or Xifyrm?

Diclofenac Sodium and Xifyrm are tied at 3.5 out of 5 by our independent rating.

What is the difference between Diclofenac Sodium and Xifyrm?

Diclofenac Sodium contains Diclofenac Sodium, while Xifyrm contains Meloxicam — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.