DICLOFENAC SODIUM vs RELAFEN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Possible drug interaction. DICLOFENAC SODIUM and RELAFEN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	DICLOFENAC SODIUM	RELAFEN
Rating	70/100	New
Pharmacy pays	$0.36 /mL	~$4.00 /30
Type	RX	RX
Active ingredient	DICLOFENAC SODIUM	NABUMETONE
Manufacturer	Amneal	Smithkline Beecham
Dosage forms	Solution, Drops, Topical, Tablet, delayed release, Tablet, extended release, Tablet, Kit	Tablet
Drug class	Nonsteroidal Anti-Inflammatory Drug	Nonsteroidal Anti-Inflammatory Drug
Boxed warning	Boxed warning	None
Half-life	about 2 hours (terminal/elimination half-life; the label's table gives a mean of 2.3 hours in healthy adults, with wide variation between people — 48% coefficient of variation)	—
Treats	Juvenile Arthritis, Rheumatoid Arthritis, Dysmenorrhea	Rheumatoid Arthritis, Inflammation, Osteoarthritis

diclofenac sodium relafen

Rating

70/100

New

Pharmacy pays

$0.36 /mL

~$4.00 /30

Type

Active ingredient

DICLOFENAC SODIUM

NABUMETONE

Manufacturer

Amneal

Smithkline Beecham

Dosage forms

Solution, Drops, Topical, Tablet, delayed release, Tablet, extended release, Tablet, Kit

Tablet

Drug class

Nonsteroidal Anti-Inflammatory Drug

Boxed warning

None

Half-life

about 2 hours (terminal/elimination half-life; the label's table gives a mean of 2.3 hours in healthy adults, with wide variation between people — 48% coefficient of variation)

—

Treats

Juvenile Arthritis, Rheumatoid Arthritis, Dysmenorrhea

Rheumatoid Arthritis, Inflammation, Osteoarthritis

Frequently asked questions

What is the difference between Diclofenac Sodium and Relafen?

Diclofenac Sodium contains Diclofenac Sodium, while Relafen contains Nabumetone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.