DICLOFENAC SODIUM vs MIDOL LIQUID GELS

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Attribute	DICLOFENAC SODIUM	MIDOL LIQUID GELS
Rating	70/100	70/100
Pharmacy pays	$0.36 /mL	$0.04 /mL
Type	RX	OTC
Active ingredient	DICLOFENAC SODIUM	IBUPROFEN
Manufacturer	Amneal	Bionpharma
Dosage forms	Solution, Drops, Topical, Tablet, delayed release, Tablet, extended release, Tablet, Kit	Capsule
Drug class	Nonsteroidal Anti-Inflammatory Drug	Nonsteroidal Anti-Inflammatory Drug
Boxed warning	Boxed warning	None
Half-life	about 2 hours (terminal/elimination half-life; the label's table gives a mean of 2.3 hours in healthy adults, with wide variation between people — 48% coefficient of variation)	about 1.8 to 2.0 hours
Treats	Juvenile Arthritis, Rheumatoid Arthritis, Dysmenorrhea	Juvenile Arthritis, Rheumatoid Arthritis, Bursitis

diclofenac sodium midol liquid gels

Rating

70/100

Pharmacy pays

$0.36 /mL

$0.04 /mL

Type

OTC

Active ingredient

DICLOFENAC SODIUM

IBUPROFEN

Manufacturer

Amneal

Bionpharma

Dosage forms

Solution, Drops, Topical, Tablet, delayed release, Tablet, extended release, Tablet, Kit

Capsule

Drug class

Nonsteroidal Anti-Inflammatory Drug

Boxed warning

None

Half-life

about 2 hours (terminal/elimination half-life; the label's table gives a mean of 2.3 hours in healthy adults, with wide variation between people — 48% coefficient of variation)

about 1.8 to 2.0 hours

Treats

Juvenile Arthritis, Rheumatoid Arthritis, Dysmenorrhea

Juvenile Arthritis, Rheumatoid Arthritis, Bursitis

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Where to buy

Buy over-the-counter from trusted retailers.

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Frequently asked questions

Which is better-rated, Diclofenac Sodium or Midol Liquid Gels?

Diclofenac Sodium and Midol Liquid Gels are tied at 3.5 out of 5 by our independent rating.

Which is cheaper, Diclofenac Sodium or Midol Liquid Gels?

Midol Liquid Gels costs pharmacies less to acquire — about $0.04 vs $0.36 per ml, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Diclofenac Sodium and Midol Liquid Gels?

Diclofenac Sodium contains Diclofenac Sodium, while Midol Liquid Gels contains Ibuprofen — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.