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DICLOFENAC SODIUM vs JUNIOR STRENGTH ADVIL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Rating

70/100
72/100

Pharmacy pays

$0.36 /mL
$0.04 /mL

Type

RX
OTC

Active ingredient

DICLOFENAC SODIUM
IBUPROFEN

Dosage forms

Solution, Drops, Topical, Tablet, delayed release, Tablet, extended release, Tablet, Kit
Tablet, chewable, Tablet

Drug class

Nonsteroidal Anti-Inflammatory Drug
Nonsteroidal Anti-Inflammatory Drug

Boxed warning

Half-life

about 2 hours (terminal/elimination half-life; the label's table gives a mean of 2.3 hours in healthy adults, with wide variation between people — 48% coefficient of variation)
about 1.8 to 2.0 hours

Treats

Juvenile Arthritis, Rheumatoid Arthritis, Dysmenorrhea
Juvenile Arthritis, Rheumatoid Arthritis, Bursitis

Get junior strength advilhigher-rated option

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Where to buy

Buy over-the-counter from trusted retailers.

Frequently asked questions

Which is better-rated, Diclofenac Sodium or Junior Strength Advil?

By our independent rating, Junior Strength Advil scores higher — 3.6 vs 3.5 out of 5 for Diclofenac Sodium. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Diclofenac Sodium or Junior Strength Advil?

Junior Strength Advil costs pharmacies less to acquire — about $0.04 vs $0.36 per ml, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Diclofenac Sodium and Junior Strength Advil?

Diclofenac Sodium contains Diclofenac Sodium, while Junior Strength Advil contains Ibuprofen — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.