DIAZEPAM vs LORAZEPAM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. DIAZEPAM and LORAZEPAM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	DIAZEPAM	LORAZEPAM
Rating	68/100	70/100
Pharmacy pays	~$0.87 /30	~$1.14 /30
Type	RX	RX
Active ingredient	DIAZEPAM	LORAZEPAM
Manufacturer	Aurobindo Pharma Ltd	Ani Pharms
Dosage forms	Injectable, Tablet	Injectable, Solution, Liquid, Tablet
Drug class	Benzodiazepine	Benzodiazepine
Boxed warning	Boxed warning	Boxed warning
Half-life	about 48 hours (up to 48 hours), but it varies strongly with age — roughly 20 hours at age 20 and rising by about 1 hour for each year of age	about 12 hours (mean)
Treats	Alcohol Withdrawal Delirium, Muscle Spasticity, Status Epilepticus	Anxiety Disorders, Catatonia, Depressive Disorder

diazepam lorazepam

Rating

68/100

70/100

Pharmacy pays

~$0.87 /30

~$1.14 /30

Type

Active ingredient

DIAZEPAM

LORAZEPAM

Manufacturer

Aurobindo Pharma Ltd

Ani Pharms

Dosage forms

Injectable, Tablet

Injectable, Solution, Liquid, Tablet

Drug class

Benzodiazepine

Boxed warning

Half-life

about 48 hours (up to 48 hours), but it varies strongly with age — roughly 20 hours at age 20 and rising by about 1 hour for each year of age

about 12 hours (mean)

Treats

Alcohol Withdrawal Delirium, Muscle Spasticity, Status Epilepticus

Anxiety Disorders, Catatonia, Depressive Disorder

Frequently asked questions

Which is better-rated, Diazepam or Lorazepam?

By our independent rating, Lorazepam scores higher — 3.5 vs 3.4 out of 5 for Diazepam. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Diazepam or Lorazepam?

Diazepam costs pharmacies less to acquire — about $0.87 vs $1.14 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Diazepam and Lorazepam?

Diazepam contains Diazepam, while Lorazepam contains Lorazepam — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.