DIASTAT vs LIBRELEASE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 12, 2026·How we rate

Possible drug interaction. DIASTAT and LIBRELEASE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	DIASTAT	LIBRELEASE
Rating	New	70/100
Pharmacy pays	~$0.87 /30	~$4.83 /30
Type	RX	RX
Active ingredient	DIAZEPAM	CHLORDIAZEPOXIDE
Manufacturer	Bausch	Valeant Pharm Intl
Dosage forms	Topical	Capsule, extended release
Drug class	Benzodiazepine	Benzodiazepine
Boxed warning	Boxed warning	None
Half-life	about 48 hours (up to 48 hours), but it varies strongly with age — roughly 20 hours at age 20 and rising by about 1 hour for each year of age	—
Treats	Alcohol Withdrawal Delirium, Muscle Spasticity, Status Epilepticus	Alcohol Withdrawal Delirium, Anxiety Disorders

diastat librelease

Rating

New

70/100

Pharmacy pays

~$0.87 /30

~$4.83 /30

Type

Active ingredient

DIAZEPAM

CHLORDIAZEPOXIDE

Manufacturer

Bausch

Valeant Pharm Intl

Dosage forms

Topical

Capsule, extended release

Drug class

Benzodiazepine

Boxed warning

None

Half-life

about 48 hours (up to 48 hours), but it varies strongly with age — roughly 20 hours at age 20 and rising by about 1 hour for each year of age

—

Treats

Alcohol Withdrawal Delirium, Muscle Spasticity, Status Epilepticus

Alcohol Withdrawal Delirium, Anxiety Disorders

Frequently asked questions

Which is cheaper, Diastat or Librelease?

Diastat costs pharmacies less to acquire — about $0.87 vs $4.83 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Diastat and Librelease?

Diastat contains Diazepam, while Librelease contains Chlordiazepoxide — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.