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DIASTAT ACUDIAL vs ONFI

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. DIASTAT ACUDIAL and ONFI are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

New
New

Pharmacy pays

~$0.87 /30
~$7.72 /30

Type

RX
RX

Active ingredient

DIAZEPAM
CLOBAZAM

Dosage forms

Topical
Suspension, Tablet

Drug class

Benzodiazepine
Benzodiazepine

Half-life

about 48 hours (up to 48 hours), but it varies strongly with age — roughly 20 hours at age 20 and rising by about 1 hour for each year of age

Treats

Alcohol Withdrawal Delirium, Muscle Spasticity, Status Epilepticus
Seizures, Lennox Gastaut Syndrome

Frequently asked questions

Which is cheaper, Diastat Acudial or Onfi?

Diastat Acudial costs pharmacies less to acquire — about $0.87 vs $7.72 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Diastat Acudial and Onfi?

Diastat Acudial contains Diazepam, while Onfi contains Clobazam — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.