DIASTAT ACUDIAL vs LOREEV XR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. DIASTAT ACUDIAL and LOREEV XR are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	DIASTAT ACUDIAL	LOREEV XR
Rating	New	New
Pharmacy pays	~$0.87 /30	~$1.14 /30
Type	RX	RX
Active ingredient	DIAZEPAM	LORAZEPAM
Manufacturer	Bausch	Almatica
Dosage forms	Topical	Capsule, extended release
Drug class	Benzodiazepine	Benzodiazepine
Boxed warning	Boxed warning	Boxed warning
Half-life	about 48 hours (up to 48 hours), but it varies strongly with age — roughly 20 hours at age 20 and rising by about 1 hour for each year of age	about 12 hours (mean)
Treats	Alcohol Withdrawal Delirium, Muscle Spasticity, Status Epilepticus	Anxiety Disorders, Catatonia, Depressive Disorder

diastat acudial loreev xr

Rating

New

Pharmacy pays

~$0.87 /30

~$1.14 /30

Type

Active ingredient

DIAZEPAM

LORAZEPAM

Manufacturer

Bausch

Almatica

Dosage forms

Topical

Capsule, extended release

Drug class

Benzodiazepine

Boxed warning

Half-life

about 48 hours (up to 48 hours), but it varies strongly with age — roughly 20 hours at age 20 and rising by about 1 hour for each year of age

about 12 hours (mean)

Treats

Alcohol Withdrawal Delirium, Muscle Spasticity, Status Epilepticus

Anxiety Disorders, Catatonia, Depressive Disorder

Frequently asked questions

Which is cheaper, Diastat Acudial or Loreev XR?

Diastat Acudial costs pharmacies less to acquire — about $0.87 vs $1.14 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Diastat Acudial and Loreev XR?

Diastat Acudial contains Diazepam, while Loreev XR contains Lorazepam — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.