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DIABETA vs GLIMEPIRIDE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. DIABETA and GLIMEPIRIDE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

70/100
New

Pharmacy pays

~$1.97 /30
~$1.00 /30

Type

RX
RX

Active ingredient

GLYBURIDE
GLIMEPIRIDE

Dosage forms

Tablet
Tablet

Drug class

Sulfonylurea
Sulfonylurea

Boxed warning

None
None

Half-life

about 10 hours (terminal/elimination half-life)
about 5 hours (label mean 5.3 hours in adults, ± 4.1 hours — variation between people is wide)

Treats

Type 2 Diabetes Mellitus
Type 2 Diabetes Mellitus

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Frequently asked questions

Which is cheaper, Diabeta or Glimepiride?

Glimepiride costs pharmacies less to acquire — about $1.00 vs $1.97 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Diabeta and Glimepiride?

Diabeta contains Glyburide, while Glimepiride contains Glimepiride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.