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DEXTROAMPHETAMINE SULFATE vs MODAFINIL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. DEXTROAMPHETAMINE SULFATE and MODAFINIL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

dextroamphetamine sulfatemodafinil

Rating

72/100
70/100

Pharmacy pays

~$29.94 /30
~$10.47 /30

Type

RX
RX

Active ingredient

DEXTROAMPHETAMINE SULFATE
MODAFINIL

Manufacturer

Tris Pharma Inc
Appco

Dosage forms

Capsule, extended release, Solution, Tablet
Tablet

Drug class

Central Nervous System Stimulant
Sympathomimetic-Like Agent

Boxed warning

Boxed warning
None

Treats

Attention Deficit Disorder with Hyperactivity, Narcolepsy
Attention Deficit Disorder with Hyperactivity, Fatigue, Narcolepsy

Frequently asked questions

Which is better-rated, Dextroamphetamine Sulfate or Modafinil?

By our independent rating, Dextroamphetamine Sulfate scores higher — 3.6 vs 3.5 out of 5 for Modafinil. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Dextroamphetamine Sulfate or Modafinil?

Modafinil costs pharmacies less to acquire — about $10.47 vs $29.94 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Dextroamphetamine Sulfate and Modafinil?

Dextroamphetamine Sulfate contains Dextroamphetamine Sulfate, while Modafinil contains Modafinil — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.