Skip to content
ppharmaranks
Menu
CompaniesProductsDrug classesConditionsBest by conditionTreatmentsInteraction checkerFood & medicinesWhat pharmacies payPill identifierMedicines & breastfeedingChildren’s dosage chartsDo medicines expire?Crushing & splitting pillsHow long meds take to workAlternating Tylenol & ibuprofenDrug recallsSupplementsSafety & lawsuitsGuidesA–ZHow we rate

DEXTROAMPHETAMINE SULFATE vs METHYLIN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. DEXTROAMPHETAMINE SULFATE and METHYLIN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

dextroamphetamine sulfatemethylin

Rating

72/100
70/100

Pharmacy pays

~$29.94 /30
~$18.94 /30

Type

RX
RX

Active ingredient

DEXTROAMPHETAMINE SULFATE
METHYLPHENIDATE HYDROCHLORIDE

Manufacturer

Tris Pharma Inc
Specgx LLC

Dosage forms

Capsule, extended release, Solution, Tablet
Solution

Drug class

Central Nervous System Stimulant
Central Nervous System Stimulant

Boxed warning

Boxed warning
Boxed warning

Half-life

—
about 2.7 hours

Treats

Attention Deficit Disorder with Hyperactivity, Narcolepsy
Attention Deficit Disorder with Hyperactivity, Depressive Disorder, Narcolepsy

Frequently asked questions

Which is better-rated, Dextroamphetamine Sulfate or Methylin?

By our independent rating, Dextroamphetamine Sulfate scores higher — 3.6 vs 3.5 out of 5 for Methylin. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Dextroamphetamine Sulfate or Methylin?

Methylin costs pharmacies less to acquire — about $18.94 vs $29.94 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Dextroamphetamine Sulfate and Methylin?

Dextroamphetamine Sulfate contains Dextroamphetamine Sulfate, while Methylin contains Methylphenidate Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.