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DEXEDRINE SPANSULE vs FOCALIN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. DEXEDRINE SPANSULE and FOCALIN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

dexedrine spansulefocalin

Rating

70/100
68/100

Pharmacy pays

~$29.94 /30
~$46.03 /30

Type

RX
RX

Active ingredient

DEXTROAMPHETAMINE SULFATE
DEXMETHYLPHENIDATE HYDROCHLORIDE

Manufacturer

Impax
Sandoz

Dosage forms

Capsule, extended release
Tablet

Drug class

Central Nervous System Stimulant
Central Nervous System Stimulant

Boxed warning

Boxed warning
Boxed warning

Treats

Attention Deficit Disorder with Hyperactivity, Narcolepsy
Attention Deficit Disorder with Hyperactivity

Frequently asked questions

Which is better-rated, Dexedrine Spansule or Focalin?

By our independent rating, Dexedrine Spansule scores higher — 3.5 vs 3.4 out of 5 for Focalin. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Dexedrine Spansule or Focalin?

Dexedrine Spansule costs pharmacies less to acquire — about $29.94 vs $46.03 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Dexedrine Spansule and Focalin?

Dexedrine Spansule contains Dextroamphetamine Sulfate, while Focalin contains Dexmethylphenidate Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.