DEXEDRINE SPANSULE vs EVEKEO ODT

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Possible drug interaction. DEXEDRINE SPANSULE and EVEKEO ODT are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	DEXEDRINE SPANSULE	EVEKEO ODT
Rating	70/100	70/100
Pharmacy pays	~$29.94 /30	~$478.55 /30
Type	RX	RX
Active ingredient	DEXTROAMPHETAMINE SULFATE	AMPHETAMINE SULFATE
Manufacturer	Impax	Azurity
Dosage forms	Capsule, extended release	Tablet, orally disintegrating
Drug class	Central Nervous System Stimulant	Central Nervous System Stimulant
Boxed warning	Boxed warning	None
Half-life	—	about 10 to 11 hours for d-amphetamine (range 9.8 to 11 hours) and about 12 to 14 hours for l-amphetamine (range 11.5 to 13.8 hours) in healthy adults
Treats	Attention Deficit Disorder with Hyperactivity, Narcolepsy	Attention Deficit Disorder with Hyperactivity, Narcolepsy

dexedrine spansule evekeo odt

Rating

70/100

Pharmacy pays

~$29.94 /30

~$478.55 /30

Type

Active ingredient

DEXTROAMPHETAMINE SULFATE

AMPHETAMINE SULFATE

Manufacturer

Impax

Azurity

Dosage forms

Capsule, extended release

Tablet, orally disintegrating

Drug class

Central Nervous System Stimulant

Boxed warning

None

Half-life

—

about 10 to 11 hours for d-amphetamine (range 9.8 to 11 hours) and about 12 to 14 hours for l-amphetamine (range 11.5 to 13.8 hours) in healthy adults

Treats

Attention Deficit Disorder with Hyperactivity, Narcolepsy

Frequently asked questions

Which is better-rated, Dexedrine Spansule or Evekeo ODT?

Dexedrine Spansule and Evekeo ODT are tied at 3.5 out of 5 by our independent rating.

Which is cheaper, Dexedrine Spansule or Evekeo ODT?

Dexedrine Spansule costs pharmacies less to acquire — about $29.94 vs $478.55 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Dexedrine Spansule and Evekeo ODT?

Dexedrine Spansule contains Dextroamphetamine Sulfate, while Evekeo ODT contains Amphetamine Sulfate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.