DESVENLAFAXINE SUCCINATE vs FETZIMA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 9, 2026·How we rate

Possible drug interaction. DESVENLAFAXINE SUCCINATE and FETZIMA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	DESVENLAFAXINE SUCCINATE	FETZIMA
Rating	72/100	72/100
Pharmacy pays	~$115.22 /30	—
Type	RX	RX
Active ingredient	DESVENLAFAXINE SUCCINATE	LEVOMILNACIPRAN HYDROCHLORIDE
Manufacturer	Actavis Labs Fl Inc	Abbvie
Dosage forms	Tablet, extended release	Capsule, extended release, Kit
Drug class	Serotonin and Norepinephrine Reuptake Inhibitor	Serotonin and Norepinephrine Reuptake Inhibitor
Boxed warning	Boxed warning	Boxed warning
Half-life	—	about 12 hours
Treats	Major Depressive Disorder	Major Depressive Disorder

desvenlafaxine succinate fetzima

Rating

72/100

Pharmacy pays

~$115.22 /30

—

Type

Active ingredient

DESVENLAFAXINE SUCCINATE

LEVOMILNACIPRAN HYDROCHLORIDE

Manufacturer

Actavis Labs Fl Inc

Abbvie

Dosage forms

Tablet, extended release

Capsule, extended release, Kit

Drug class

Serotonin and Norepinephrine Reuptake Inhibitor

Boxed warning

Half-life

—

about 12 hours

Treats

Major Depressive Disorder

Frequently asked questions

Which is better-rated, Desvenlafaxine Succinate or Fetzima?

Desvenlafaxine Succinate and Fetzima are tied at 3.6 out of 5 by our independent rating.

What is the difference between Desvenlafaxine Succinate and Fetzima?

Desvenlafaxine Succinate contains Desvenlafaxine Succinate, while Fetzima contains Levomilnacipran Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.