DESVENLAFAXINE SUCCINATE vs EFFEXOR XR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. DESVENLAFAXINE SUCCINATE and EFFEXOR XR are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	DESVENLAFAXINE SUCCINATE	EFFEXOR XR
Rating	70/100	New
Pharmacy pays	~$115.24 /30	~$3.59 /30
Type	RX	RX
Active ingredient	DESVENLAFAXINE SUCCINATE	VENLAFAXINE HYDROCHLORIDE
Manufacturer	Actavis Labs Fl Inc	Upjohn
Dosage forms	Tablet, extended release	Capsule, extended release
Drug class	Serotonin and Norepinephrine Reuptake Inhibitor	Serotonin and Norepinephrine Reuptake Inhibitor
Boxed warning	Boxed warning	Boxed warning
Half-life	—	about 5 hours (mean roughly 5 ± 2 hours) for the parent drug venlafaxine in adults with normal organ function
Treats	Major Depressive Disorder	Attention Deficit Disorder with Hyperactivity, Autistic Disorder, Depressive Disorder

desvenlafaxine succinate effexor xr

Rating

70/100

New

Pharmacy pays

~$115.24 /30

~$3.59 /30

Type

Active ingredient

DESVENLAFAXINE SUCCINATE

VENLAFAXINE HYDROCHLORIDE

Manufacturer

Actavis Labs Fl Inc

Upjohn

Dosage forms

Tablet, extended release

Capsule, extended release

Drug class

Serotonin and Norepinephrine Reuptake Inhibitor

Boxed warning

Half-life

—

about 5 hours (mean roughly 5 ± 2 hours) for the parent drug venlafaxine in adults with normal organ function

Treats

Major Depressive Disorder

Attention Deficit Disorder with Hyperactivity, Autistic Disorder, Depressive Disorder

Get effexor xr

Advertising disclosure: Some links are affiliate links. We may earn a commission at no extra cost to you. This never affects our independent ratings.

Get treatment online

Licensed online providers — consult & get prescribed if eligible.

SesameCompare online visit prices

Frequently asked questions

Which is cheaper, Desvenlafaxine Succinate or Effexor XR?

Effexor XR costs pharmacies less to acquire — about $3.59 vs $115.24 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Desvenlafaxine Succinate and Effexor XR?

Desvenlafaxine Succinate contains Desvenlafaxine Succinate, while Effexor XR contains Venlafaxine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.