DESOXIMETASONE vs LOCOID LIPOCREAM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Possible drug interaction. DESOXIMETASONE and LOCOID LIPOCREAM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	DESOXIMETASONE	LOCOID LIPOCREAM
Rating	72/100	New
Pharmacy pays	$0.40 /g	—
Type	RX	RX
Active ingredient	DESOXIMETASONE	HYDROCORTISONE BUTYRATE
Manufacturer	Rising	Precision Dermat
Dosage forms	Topical	Topical
Drug class	Corticosteroid	Corticosteroid
Boxed warning	None	None
Half-life	—	about 1.5 hours
Treats	Facial Dermatoses, Foot Dermatoses, Hand Dermatoses	Adrenal Insufficiency, Congenital Adrenal Hyperplasia, Ulcerative Colitis

desoximetasone locoid lipocream

Rating

72/100

New

Pharmacy pays

$0.40 /g

—

Type

Active ingredient

DESOXIMETASONE

HYDROCORTISONE BUTYRATE

Manufacturer

Rising

Precision Dermat

Dosage forms

Topical

Drug class

Corticosteroid

Boxed warning

None

Half-life

—

about 1.5 hours

Treats

Facial Dermatoses, Foot Dermatoses, Hand Dermatoses

Adrenal Insufficiency, Congenital Adrenal Hyperplasia, Ulcerative Colitis

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Frequently asked questions

What is the difference between Desoximetasone and Locoid Lipocream?

Desoximetasone contains Desoximetasone, while Locoid Lipocream contains Hydrocortisone Butyrate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.