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DESIPRAMINE HYDROCHLORIDE vs IMIPRAMINE HYDROCHLORIDE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 16, 2026·How we rate

Possible drug interaction. DESIPRAMINE HYDROCHLORIDE and IMIPRAMINE HYDROCHLORIDE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

desipramine hydrochlorideimipramine hydrochloride

Rating

70/100
70/100

Pharmacy pays

~$8.39 /30
~$2.54 /30

Type

RX
RX

Active ingredient

DESIPRAMINE HYDROCHLORIDE
IMIPRAMINE HYDROCHLORIDE

Manufacturer

Ani Pharms
Strides Pharma Intl

Dosage forms

Tablet
Tablet

Drug class

Tricyclic Antidepressant
Tricyclic Antidepressant

Boxed warning

None
Boxed warning

Treats

Attention Deficit Disorder with Hyperactivity, Depressive Disorder, Pain
Attention Deficit Disorder with Hyperactivity, Depressive Disorder, Enuresis

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Frequently asked questions

Which is better-rated, Desipramine Hydrochloride or Imipramine Hydrochloride?

Desipramine Hydrochloride and Imipramine Hydrochloride are tied at 3.5 out of 5 by our independent rating.

Which is cheaper, Desipramine Hydrochloride or Imipramine Hydrochloride?

Imipramine Hydrochloride costs pharmacies less to acquire — about $2.54 vs $8.39 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Desipramine Hydrochloride and Imipramine Hydrochloride?

Desipramine Hydrochloride contains Desipramine Hydrochloride, while Imipramine Hydrochloride contains Imipramine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.