DEPO-PROVERA vs DEPO-SUBQ PROVERA 104

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Attribute	DEPO-PROVERA	DEPO-SUBQ PROVERA 104
Rating	64/100	64/100
Pharmacy pays	~$562.79 /30	~$562.79 /30
Type	RX	RX
Active ingredient	MEDROXYPROGESTERONE ACETATE	MEDROXYPROGESTERONE ACETATE
Manufacturer	Pfizer	Pfizer
Dosage forms	Injectable	Injectable
Drug class	Progestin	Progestin
Boxed warning	Boxed warning	Boxed warning
Treats	Amenorrhea, Breast Neoplasms, Renal Cell Carcinoma	Amenorrhea, Breast Neoplasms, Renal Cell Carcinoma

depo-provera depo-subq provera 104

Rating

64/100

Pharmacy pays

~$562.79 /30

Type

Active ingredient

MEDROXYPROGESTERONE ACETATE

Manufacturer

Pfizer

Dosage forms

Injectable

Drug class

Progestin

Boxed warning

Treats

Amenorrhea, Breast Neoplasms, Renal Cell Carcinoma

Frequently asked questions

Which is better-rated, Depo-Provera or Depo-Subq Provera 104?

Depo-Provera and Depo-Subq Provera 104 are tied at 3.2 out of 5 by our independent rating.

Which is cheaper, Depo-Provera or Depo-Subq Provera 104?

Pharmacies pay about the same to acquire either one — roughly $562.79 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Depo-Provera and Depo-Subq Provera 104?

Both Depo-Provera and Depo-Subq Provera 104 share the active ingredient Medroxyprogesterone Acetate.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.