DEPO-MEDROL vs MEDROL ACETATE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 12, 2026·How we rate

Attribute	DEPO-MEDROL	MEDROL ACETATE
Rating	56/100	New
Pharmacy pays	~$30.69 /30	~$30.69 /30
Type	RX	RX
Active ingredient	METHYLPREDNISOLONE ACETATE	METHYLPREDNISOLONE ACETATE
Manufacturer	Pfizer	Pharmacia and Upjohn
Dosage forms	Injectable	Topical
Drug class	Corticosteroid	Corticosteroid
Boxed warning	None	None
Treats	Adrenal Insufficiency, Asthma, Berylliosis	Adrenal Insufficiency, Asthma, Berylliosis

depo-medrol medrol acetate

Rating

56/100

New

Pharmacy pays

~$30.69 /30

Type

Active ingredient

METHYLPREDNISOLONE ACETATE

Manufacturer

Pfizer

Pharmacia and Upjohn

Dosage forms

Injectable

Topical

Drug class

Corticosteroid

Boxed warning

None

Treats

Adrenal Insufficiency, Asthma, Berylliosis

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Frequently asked questions

Which is cheaper, Depo-Medrol or Medrol Acetate?

Pharmacies pay about the same to acquire either one — roughly $30.69 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Depo-Medrol and Medrol Acetate?

Both Depo-Medrol and Medrol Acetate share the active ingredient Methylprednisolone Acetate.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.