DEPAKOTE vs DIVALPROEX SODIUM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Attribute	DEPAKOTE	DIVALPROEX SODIUM
Rating	72/100	68/100
Pharmacy pays	~$5.99 /30	~$5.99 /30
Type	RX	RX
Active ingredient	DIVALPROEX SODIUM	DIVALPROEX SODIUM
Manufacturer	Abbvie	Aurobindo Pharma Ltd
Dosage forms	Tablet, delayed release	Capsule, Oral pellets, Capsule, delayed release, Tablet, delayed release, Tablet, extended release
Drug class	Anti-Epileptic Agent	Anti-Epileptic Agent
Boxed warning	Boxed warning	Boxed warning
Half-life	about 9 to 16 hours (the label's mean terminal half-life range for valproate monotherapy)	about 9 to 16 hours (the label's mean terminal half-life range for valproate monotherapy)
Treats	Bipolar Disorder, Epilepsy, Absence Epilepsy	Bipolar Disorder, Epilepsy, Absence Epilepsy

depakote divalproex sodium

Rating

72/100

68/100

Pharmacy pays

~$5.99 /30

Type

Active ingredient

DIVALPROEX SODIUM

Manufacturer

Abbvie

Aurobindo Pharma Ltd

Dosage forms

Tablet, delayed release

Capsule, Oral pellets, Capsule, delayed release, Tablet, delayed release, Tablet, extended release

Drug class

Anti-Epileptic Agent

Boxed warning

Half-life

about 9 to 16 hours (the label's mean terminal half-life range for valproate monotherapy)

Treats

Bipolar Disorder, Epilepsy, Absence Epilepsy

Frequently asked questions

Which is better-rated, Depakote or Divalproex Sodium?

By our independent rating, Depakote scores higher — 3.6 vs 3.4 out of 5 for Divalproex Sodium. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Depakote or Divalproex Sodium?

Pharmacies pay about the same to acquire either one — roughly $5.99 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Depakote and Divalproex Sodium?

Both Depakote and Divalproex Sodium share the active ingredient Divalproex Sodium.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.