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DEPAKOTE ER vs ZYPREXA RELPREVV

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Possible drug interaction. DEPAKOTE ER and ZYPREXA RELPREVV are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

70/100
New

Pharmacy pays

~$5.99 /30

Type

RX
RX

Active ingredient

DIVALPROEX SODIUM
OLANZAPINE PAMOATE

Manufacturer

Dosage forms

Tablet, extended release
Kit

Drug class

Anti-Epileptic Agent

Boxed warning

Half-life

about 9 to 16 hours (the label's mean terminal half-life range for valproate monotherapy)
about 21 to 54 hours (mean around 30 hours)

Treats

Bipolar Disorder, Epilepsy, Absence Epilepsy
Bipolar Disorder, Psychotic Disorders, Schizophrenia

Frequently asked questions

What is the difference between Depakote ER and Zyprexa Relprevv?

Depakote ER contains Divalproex Sodium, while Zyprexa Relprevv contains Olanzapine Pamoate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.