DEPAKOTE ER vs PEGANONE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. DEPAKOTE ER and PEGANONE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	DEPAKOTE ER	PEGANONE
Rating	70/100	New
Pharmacy pays	~$5.99 /30	—
Type	RX	RX
Active ingredient	DIVALPROEX SODIUM	ETHOTOIN
Manufacturer	Abbott	Recordati Rare
Dosage forms	Tablet, extended release	Tablet
Drug class	Anti-Epileptic Agent	—
Boxed warning	None	None
Half-life	about 9 to 16 hours (the label's mean terminal half-life range for valproate monotherapy)	—
Treats	Bipolar Disorder, Epilepsy, Absence Epilepsy	Tonic-Clonic Epilepsy, Seizures, Complex Partial Epilepsy

depakote er peganone

Rating

70/100

New

Pharmacy pays

~$5.99 /30

—

Type

Active ingredient

DIVALPROEX SODIUM

ETHOTOIN

Manufacturer

Abbott

Recordati Rare

Dosage forms

Tablet, extended release

Tablet

Drug class

Anti-Epileptic Agent

—

Boxed warning

None

Half-life

about 9 to 16 hours (the label's mean terminal half-life range for valproate monotherapy)

—

Treats

Bipolar Disorder, Epilepsy, Absence Epilepsy

Tonic-Clonic Epilepsy, Seizures, Complex Partial Epilepsy

Frequently asked questions

What is the difference between Depakote ER and Peganone?

Depakote ER contains Divalproex Sodium, while Peganone contains Ethotoin — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.