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DEPAKOTE ER vs OXCARBAZEPINE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Possible drug interaction. DEPAKOTE ER and OXCARBAZEPINE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

depakote eroxcarbazepine

Rating

70/100
70/100

Pharmacy pays

~$5.99 /30
~$5.03 /30

Type

RX
RX

Active ingredient

DIVALPROEX SODIUM
OXCARBAZEPINE

Manufacturer

Abbott
Jubilant Cadista

Dosage forms

Tablet, extended release
Suspension, Tablet, extended release, Tablet

Drug class

Anti-Epileptic Agent
Anti-Epileptic Agent

Boxed warning

None
None

Half-life

about 9 to 16 hours (the label's mean terminal half-life range for valproate monotherapy)
about 2 hours (immediate-release tablets and oral suspension)

Treats

Bipolar Disorder, Epilepsy, Absence Epilepsy
Partial Epilepsies

Frequently asked questions

Which is better-rated, Depakote ER or Oxcarbazepine?

Depakote ER and Oxcarbazepine are tied at 3.5 out of 5 by our independent rating.

Which is cheaper, Depakote ER or Oxcarbazepine?

Oxcarbazepine costs pharmacies less to acquire — about $5.03 vs $5.99 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Depakote ER and Oxcarbazepine?

Depakote ER contains Divalproex Sodium, while Oxcarbazepine contains Oxcarbazepine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.