DEPAKENE vs OXTELLAR XR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 12, 2026·How we rate

Possible drug interaction. DEPAKENE and OXTELLAR XR are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	DEPAKENE	OXTELLAR XR
Rating	72/100	New
Pharmacy pays	~$1.02 /30	~$5.03 /30
Type	RX	RX
Active ingredient	VALPROIC ACID	OXCARBAZEPINE
Manufacturer	Abbvie	Supernus Pharms
Dosage forms	Syrup, Capsule	Tablet
Drug class	Anti-Epileptic Agent	Anti-Epileptic Agent
Boxed warning	None	None
Half-life	—	about 2 hours (immediate-release tablets and oral suspension)
Treats	Alzheimer Disease, Bipolar Disorder, Epilepsy	Partial Epilepsies

depakene oxtellar xr

Rating

72/100

New

Pharmacy pays

~$1.02 /30

~$5.03 /30

Type

Active ingredient

VALPROIC ACID

OXCARBAZEPINE

Manufacturer

Abbvie

Supernus Pharms

Dosage forms

Syrup, Capsule

Tablet

Drug class

Anti-Epileptic Agent

Boxed warning

None

Half-life

—

about 2 hours (immediate-release tablets and oral suspension)

Treats

Alzheimer Disease, Bipolar Disorder, Epilepsy

Partial Epilepsies

Frequently asked questions

Which is cheaper, Depakene or Oxtellar XR?

Depakene costs pharmacies less to acquire — about $1.02 vs $5.03 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Depakene and Oxtellar XR?

Depakene contains Valproic Acid, while Oxtellar XR contains Oxcarbazepine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.