DEPACON vs PHENYTOIN SODIUM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. DEPACON and PHENYTOIN SODIUM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	DEPACON	PHENYTOIN SODIUM
Rating	72/100	New
Pharmacy pays	—	$0.18 /mL
Type	RX	RX
Active ingredient	VALPROATE SODIUM	PHENYTOIN SODIUM
Manufacturer	Abbvie	Marsam Pharms LLC
Dosage forms	Injectable	Capsule, Injectable
Drug class	Anti-Epileptic Agent	Anti-Epileptic Agent
Boxed warning	None	None
Half-life	about 9 to 16 hours (the label's mean terminal, or elimination, half-life for valproate monotherapy after oral doses of 250 to 1,000 mg)	About 22 hours on average, ranging from 7 to 42 hours — but phenytoin does NOT have a single fixed half-life. It follows nonlinear, saturable (Michaelis-Menten) kinetics, so the half-life lengthens as the dose and blood level rise; the label warns that "small incremental doses may increase the half-life and produce very substantial increases in serum levels" once levels are in the upper range.
Treats	—	Tonic-Clonic Epilepsy, Temporal Lobe Epilepsy, Status Epilepticus

depacon phenytoin sodium

Rating

72/100

New

Pharmacy pays

—

$0.18 /mL

Type

Active ingredient

VALPROATE SODIUM

PHENYTOIN SODIUM

Manufacturer

Abbvie

Marsam Pharms LLC

Dosage forms

Injectable

Capsule, Injectable

Drug class

Anti-Epileptic Agent

Boxed warning

None

Half-life

about 9 to 16 hours (the label's mean terminal, or elimination, half-life for valproate monotherapy after oral doses of 250 to 1,000 mg)

About 22 hours on average, ranging from 7 to 42 hours — but phenytoin does NOT have a single fixed half-life. It follows nonlinear, saturable (Michaelis-Menten) kinetics, so the half-life lengthens as the dose and blood level rise; the label warns that "small incremental doses may increase the half-life and produce very substantial increases in serum levels" once levels are in the upper range.

Treats

—

Tonic-Clonic Epilepsy, Temporal Lobe Epilepsy, Status Epilepticus

Frequently asked questions

What is the difference between Depacon and Phenytoin Sodium?

Depacon contains Valproate Sodium, while Phenytoin Sodium contains Phenytoin Sodium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.