DEPACON vs LAMICTAL ODT

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Possible drug interaction. DEPACON and LAMICTAL ODT are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	DEPACON	LAMICTAL ODT
Rating	72/100	70/100
Pharmacy pays	—	~$4.39 /30
Type	RX	RX
Active ingredient	VALPROATE SODIUM	LAMOTRIGINE
Manufacturer	Abbvie	Glaxosmithkline
Dosage forms	Injectable	Tablet, orally disintegrating, Kit
Drug class	Anti-Epileptic Agent	Anti-Epileptic Agent
Boxed warning	None	Boxed warning
Half-life	about 9 to 16 hours (the label's mean terminal, or elimination, half-life for valproate monotherapy after oral doses of 250 to 1,000 mg)	about 25 to 33 hours in healthy adults taking no other medications — the label reports a mean elimination half-life of 32.8 hours after a single dose (individual range 14 to 103 hours) and 25.4 hours with repeat dosing (range 11.6 to 61.6 hours), since lamotrigine induces its own metabolism
Treats	—	Bipolar Disorder, Partial Epilepsies, Seizures

depacon lamictal odt

Rating

72/100

70/100

Pharmacy pays

—

~$4.39 /30

Type

Active ingredient

VALPROATE SODIUM

LAMOTRIGINE

Manufacturer

Abbvie

Glaxosmithkline

Dosage forms

Injectable

Tablet, orally disintegrating, Kit

Drug class

Anti-Epileptic Agent

Boxed warning

None

Boxed warning

Half-life

about 9 to 16 hours (the label's mean terminal, or elimination, half-life for valproate monotherapy after oral doses of 250 to 1,000 mg)

about 25 to 33 hours in healthy adults taking no other medications — the label reports a mean elimination half-life of 32.8 hours after a single dose (individual range 14 to 103 hours) and 25.4 hours with repeat dosing (range 11.6 to 61.6 hours), since lamotrigine induces its own metabolism

Treats

—

Bipolar Disorder, Partial Epilepsies, Seizures

Frequently asked questions

Which is better-rated, Depacon or Lamictal ODT?

By our independent rating, Depacon scores higher — 3.6 vs 3.5 out of 5 for Lamictal ODT. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Depacon and Lamictal ODT?

Depacon contains Valproate Sodium, while Lamictal ODT contains Lamotrigine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.