DEMEROL vs NUMORPHAN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. DEMEROL and NUMORPHAN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	DEMEROL	NUMORPHAN
Rating	60/100	72/100
Pharmacy pays	$0.16 /mL	~$36.74 /30
Type	RX	RX
Active ingredient	MEPERIDINE HYDROCHLORIDE	OXYMORPHONE HYDROCHLORIDE
Manufacturer	Hospira	Endo Pharms
Dosage forms	Injectable	Suppository
Drug class	Opioid Agonist	Opioid Agonist
Boxed warning	Boxed warning	None
Treats	Pain	Pain

demerol numorphan

Rating

60/100

72/100

Pharmacy pays

$0.16 /mL

~$36.74 /30

Type

Active ingredient

MEPERIDINE HYDROCHLORIDE

OXYMORPHONE HYDROCHLORIDE

Manufacturer

Hospira

Endo Pharms

Dosage forms

Injectable

Suppository

Drug class

Opioid Agonist

Boxed warning

None

Treats

Pain

Frequently asked questions

Which is better-rated, Demerol or Numorphan?

By our independent rating, Numorphan scores higher — 3.6 vs 3.0 out of 5 for Demerol. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Demerol and Numorphan?

Demerol contains Meperidine Hydrochloride, while Numorphan contains Oxymorphone Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.