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DEMEROL vs DURAMORPH PF

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. DEMEROL and DURAMORPH PF are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

60/100
70/100

Pharmacy pays

$0.16 /mL
$2.61 /mL

Type

RX
RX

Active ingredient

MEPERIDINE HYDROCHLORIDE
MORPHINE SULFATE

Manufacturer

Dosage forms

Injectable
Injectable, Solution

Drug class

Opioid Agonist
Opioid Agonist

Half-life

about 2 hours

Treats

Pain
Dyspnea, Intractable Pain

Frequently asked questions

Which is better-rated, Demerol or Duramorph Pf?

By our independent rating, Duramorph Pf scores higher — 3.5 vs 3.0 out of 5 for Demerol. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Demerol or Duramorph Pf?

Demerol costs pharmacies less to acquire — about $0.16 vs $2.61 per ml, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Demerol and Duramorph Pf?

Demerol contains Meperidine Hydrochloride, while Duramorph Pf contains Morphine Sulfate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.