DELTA-CORTEF vs DESOXIMETASONE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. DELTA-CORTEF and DESOXIMETASONE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	DELTA-CORTEF	DESOXIMETASONE
Rating	New	72/100
Pharmacy pays	$0.60 /mL	$0.40 /g
Type	RX	RX
Active ingredient	PREDNISOLONE	DESOXIMETASONE
Manufacturer	Pharmacia and Upjohn	Rising
Dosage forms	Tablet	Topical
Drug class	Corticosteroid	Corticosteroid
Boxed warning	None	None
Half-life	2 to 4 hours	—
Treats	Adrenal Insufficiency, Hemolytic Anemia, Asthma	Facial Dermatoses, Foot Dermatoses, Hand Dermatoses

delta-cortef desoximetasone

Rating

New

72/100

Pharmacy pays

$0.60 /mL

$0.40 /g

Type

Active ingredient

PREDNISOLONE

DESOXIMETASONE

Manufacturer

Pharmacia and Upjohn

Rising

Dosage forms

Tablet

Topical

Drug class

Corticosteroid

Boxed warning

None

Half-life

2 to 4 hours

—

Treats

Adrenal Insufficiency, Hemolytic Anemia, Asthma

Facial Dermatoses, Foot Dermatoses, Hand Dermatoses

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Frequently asked questions

What is the difference between Delta-Cortef and Desoximetasone?

Delta-Cortef contains Prednisolone, while Desoximetasone contains Desoximetasone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.