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DELSYM vs DILAUDID

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 12, 2026·How we rate

Rating

New
68/100

Pharmacy pays

$0.57 /mL

Type

OTC
RX

Active ingredient

DEXTROMETHORPHAN POLISTIREX
HYDROMORPHONE HYDROCHLORIDE

Dosage forms

Suspension, extended release
Injectable, Solution, Tablet

Drug class

Opioid Agonist

Boxed warning

Half-life

about 2.3 hours (terminal elimination half-life after an intravenous dose); after an oral dose the label reports a mean T½ of about 2.6 hours for the 8 mg tablet and 2.8 hours for the oral liquid

Treats

Cough
Cough, Postoperative Pain

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Where to buy

Buy over-the-counter from trusted retailers.

Frequently asked questions

What is the difference between Delsym and Dilaudid?

Delsym contains Dextromethorphan Polistirex, while Dilaudid contains Hydromorphone Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.