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DELALUTIN vs SKYLA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 13, 2026·How we rate

Possible drug interaction. DELALUTIN and SKYLA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

72/100
New

Pharmacy pays

~$192.31 /30

Type

RX
RX

Active ingredient

HYDROXYPROGESTERONE CAPROATE
LEVONORGESTREL

Dosage forms

Solution
IUD

Drug class

Progestin
Progestin

Boxed warning

None
None

Half-life

about 36 hours (36 ± 13 hours at steady state)

Frequently asked questions

What is the difference between Delalutin and Skyla?

Delalutin contains Hydroxyprogesterone Caproate, while Skyla contains Levonorgestrel — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.