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DAYTRANA vs XELSTRYM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 12, 2026·How we rate

Possible drug interaction. DAYTRANA and XELSTRYM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

daytranaxelstrym

Rating

54/100
68/100

Pharmacy pays

~$18.94 /30
~$29.94 /30

Type

RX
RX

Active ingredient

METHYLPHENIDATE
DEXTROAMPHETAMINE

Manufacturer

Noven Pharms Inc
Noven Pharms Inc

Dosage forms

Patch
Patch, extended release

Drug class

Central Nervous System Stimulant
Central Nervous System Stimulant

Boxed warning

Boxed warning
Boxed warning

Half-life

about 2.7 hours
—

Treats

Attention Deficit Disorder with Hyperactivity, Depressive Disorder, Narcolepsy
Attention Deficit Disorder with Hyperactivity, Narcolepsy

Frequently asked questions

Which is better-rated, Daytrana or Xelstrym?

By our independent rating, Xelstrym scores higher — 3.4 vs 2.7 out of 5 for Daytrana. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Daytrana or Xelstrym?

Daytrana costs pharmacies less to acquire — about $18.94 vs $29.94 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Daytrana and Xelstrym?

Daytrana contains Methylphenidate, while Xelstrym contains Dextroamphetamine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.