DAYTRANA vs VYVANSE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. DAYTRANA and VYVANSE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	DAYTRANA	VYVANSE
Rating	54/100	New
Pharmacy pays	~$18.94 /30	—
Type	RX	RX
Active ingredient	METHYLPHENIDATE	LISDEXAMFETAMINE DIMESYLATE
Manufacturer	Noven Pharms Inc	Takeda Pharms USA
Dosage forms	Patch	Capsule, Tablet, chewable
Drug class	Central Nervous System Stimulant	Central Nervous System Stimulant
Boxed warning	Boxed warning	Boxed warning
Half-life	about 2.7 hours	less than 1 hour (parent drug)
Treats	Attention Deficit Disorder with Hyperactivity, Depressive Disorder, Narcolepsy	Attention Deficit Disorder with Hyperactivity, Binge Drinking

daytrana vyvanse

Rating

54/100

New

Pharmacy pays

~$18.94 /30

—

Type

Active ingredient

METHYLPHENIDATE

LISDEXAMFETAMINE DIMESYLATE

Manufacturer

Noven Pharms Inc

Takeda Pharms USA

Dosage forms

Patch

Capsule, Tablet, chewable

Drug class

Central Nervous System Stimulant

Boxed warning

Half-life

about 2.7 hours

less than 1 hour (parent drug)

Treats

Attention Deficit Disorder with Hyperactivity, Depressive Disorder, Narcolepsy

Attention Deficit Disorder with Hyperactivity, Binge Drinking

Frequently asked questions

What is the difference between Daytrana and Vyvanse?

Daytrana contains Methylphenidate, while Vyvanse contains Lisdexamfetamine Dimesylate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.