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DAYTRANA vs FOCALIN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. DAYTRANA and FOCALIN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

54/100
68/100

Pharmacy pays

~$18.94 /30
~$46.03 /30

Type

RX
RX

Active ingredient

METHYLPHENIDATE
DEXMETHYLPHENIDATE HYDROCHLORIDE

Dosage forms

Patch
Tablet

Drug class

Central Nervous System Stimulant
Central Nervous System Stimulant

Half-life

about 2.7 hours

Treats

Attention Deficit Disorder with Hyperactivity, Depressive Disorder, Narcolepsy
Attention Deficit Disorder with Hyperactivity

Frequently asked questions

Which is better-rated, Daytrana or Focalin?

By our independent rating, Focalin scores higher — 3.4 vs 2.7 out of 5 for Daytrana. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Daytrana or Focalin?

Daytrana costs pharmacies less to acquire — about $18.94 vs $46.03 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Daytrana and Focalin?

Daytrana contains Methylphenidate, while Focalin contains Dexmethylphenidate Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.