DAYPRO vs NAPROXEN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Possible drug interaction. DAYPRO and NAPROXEN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	DAYPRO	NAPROXEN
Rating	64/100	72/100
Pharmacy pays	~$17.64 /30	$0.06 /mL
Type	RX	RX
Active ingredient	OXAPROZIN	NAPROXEN
Manufacturer	Pfizer	Hikma
Dosage forms	Tablet	Tablet
Drug class	Nonsteroidal Anti-Inflammatory Drug	Nonsteroidal Anti-Inflammatory Drug
Boxed warning	None	Boxed warning
Half-life	—	about 12 to 17 hours
Treats	Juvenile Arthritis, Rheumatoid Arthritis, Osteoarthritis	Juvenile Arthritis, Rheumatoid Arthritis, Back Pain

daypro naproxen

Rating

64/100

72/100

Pharmacy pays

~$17.64 /30

$0.06 /mL

Type

Active ingredient

OXAPROZIN

NAPROXEN

Manufacturer

Pfizer

Hikma

Dosage forms

Tablet

Drug class

Nonsteroidal Anti-Inflammatory Drug

Boxed warning

None

Boxed warning

Half-life

—

about 12 to 17 hours

Treats

Juvenile Arthritis, Rheumatoid Arthritis, Osteoarthritis

Juvenile Arthritis, Rheumatoid Arthritis, Back Pain

Frequently asked questions

Which is better-rated, Daypro or Naproxen?

By our independent rating, Naproxen scores higher — 3.6 vs 3.2 out of 5 for Daypro. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Daypro and Naproxen?

Daypro contains Oxaprozin, while Naproxen contains Naproxen — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.