DAYPRO ALTA vs VOLTAREN-XR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. DAYPRO ALTA and VOLTAREN-XR are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	DAYPRO ALTA	VOLTAREN-XR
Rating	64/100	70/100
Pharmacy pays	~$17.64 /30	$0.36 /mL
Type	RX	RX
Active ingredient	OXAPROZIN POTASSIUM	DICLOFENAC SODIUM
Manufacturer	Pfizer	Novartis
Dosage forms	Tablet	Tablet, extended release
Drug class	Nonsteroidal Anti-Inflammatory Drug	Nonsteroidal Anti-Inflammatory Drug
Boxed warning	None	None
Half-life	—	about 2 hours (terminal/elimination half-life; the label's table gives a mean of 2.3 hours in healthy adults, with wide variation between people — 48% coefficient of variation)
Treats	Juvenile Arthritis, Rheumatoid Arthritis, Osteoarthritis	Juvenile Arthritis, Rheumatoid Arthritis, Dysmenorrhea

daypro alta voltaren-xr

Rating

64/100

70/100

Pharmacy pays

~$17.64 /30

$0.36 /mL

Type

Active ingredient

OXAPROZIN POTASSIUM

DICLOFENAC SODIUM

Manufacturer

Pfizer

Novartis

Dosage forms

Tablet

Tablet, extended release

Drug class

Nonsteroidal Anti-Inflammatory Drug

Boxed warning

None

Half-life

—

about 2 hours (terminal/elimination half-life; the label's table gives a mean of 2.3 hours in healthy adults, with wide variation between people — 48% coefficient of variation)

Treats

Juvenile Arthritis, Rheumatoid Arthritis, Osteoarthritis

Juvenile Arthritis, Rheumatoid Arthritis, Dysmenorrhea

Frequently asked questions

Which is better-rated, Daypro Alta or Voltaren-XR?

By our independent rating, Voltaren-XR scores higher — 3.5 vs 3.2 out of 5 for Daypro Alta. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Daypro Alta and Voltaren-XR?

Daypro Alta contains Oxaprozin Potassium, while Voltaren-XR contains Diclofenac Sodium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.