DARZALEX vs LENALIDOMIDE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. DARZALEX and LENALIDOMIDE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	DARZALEX	LENALIDOMIDE
Rating	New	70/100
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	DARATUMUMAB	LENALIDOMIDE
Manufacturer	Janssen Biotech	Cipla
Dosage forms	Injectable	Capsule
Drug class	—	Thalidomide Analog
Boxed warning	None	Boxed warning
Half-life	—	about 3 hours in healthy subjects, and 3 to 5 hours in patients with multiple myeloma, MDS, or mantle cell lymphoma
Treats	Multiple Myeloma	Multiple Myeloma, Myelodysplastic Syndromes, Mantle-Cell Lymphoma

darzalex lenalidomide

Rating

New

70/100

Pharmacy pays

—

Type

Active ingredient

DARATUMUMAB

LENALIDOMIDE

Manufacturer

Janssen Biotech

Cipla

Dosage forms

Injectable

Capsule

Drug class

—

Thalidomide Analog

Boxed warning

None

Boxed warning

Half-life

—

about 3 hours in healthy subjects, and 3 to 5 hours in patients with multiple myeloma, MDS, or mantle cell lymphoma

Treats

Multiple Myeloma

Multiple Myeloma, Myelodysplastic Syndromes, Mantle-Cell Lymphoma

Frequently asked questions

What is the difference between Darzalex and Lenalidomide?

Darzalex contains Daratumumab, while Lenalidomide contains Lenalidomide — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.