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DARUNAVIR vs REYATAZ

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Possible drug interaction. DARUNAVIR and REYATAZ are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

70/100
72/100

Pharmacy pays

~$49.71 /30
~$52.63 /30

Type

RX
RX

Active ingredient

DARUNAVIR
ATAZANAVIR SULFATE

Dosage forms

Tablet
Capsule, Powder

Drug class

Protease Inhibitor
Protease Inhibitor

Boxed warning

None
None

Treats

Acquired Immunodeficiency Syndrome, Hiv Infections
Acquired Immunodeficiency Syndrome

Frequently asked questions

Which is better-rated, Darunavir or Reyataz?

By our independent rating, Reyataz scores higher — 3.6 vs 3.5 out of 5 for Darunavir. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Darunavir or Reyataz?

Darunavir costs pharmacies less to acquire — about $49.71 vs $52.63 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Darunavir and Reyataz?

Darunavir contains Darunavir, while Reyataz contains Atazanavir Sulfate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.