D.H.E. 45 vs MEDIHALER ERGOTAMINE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. D.H.E. 45 and MEDIHALER ERGOTAMINE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	D.H.E. 45	MEDIHALER ERGOTAMINE
Rating	New	New
Pharmacy pays	$34.84 /mL	—
Type	RX	RX
Active ingredient	DIHYDROERGOTAMINE MESYLATE	ERGOTAMINE TARTRATE
Manufacturer	Bausch	3m
Dosage forms	Injectable	Spray/Inhaler, metered
Drug class	Ergotamine Derivative	Ergotamine Derivative
Boxed warning	None	None
Half-life	about 9 to 13 hours, depending on the form	—
Treats	Cluster Headache, Postpartum Hemorrhage, Orthostatic Hypotension	Cluster Headache, Migraine Disorders, Postpartum Hemorrhage

d.h.e. 45 medihaler ergotamine

Rating

New

Pharmacy pays

$34.84 /mL

—

Type

Active ingredient

DIHYDROERGOTAMINE MESYLATE

ERGOTAMINE TARTRATE

Manufacturer

Bausch

Dosage forms

Injectable

Spray/Inhaler, metered

Drug class

Ergotamine Derivative

Boxed warning

None

Half-life

about 9 to 13 hours, depending on the form

—

Treats

Cluster Headache, Postpartum Hemorrhage, Orthostatic Hypotension

Cluster Headache, Migraine Disorders, Postpartum Hemorrhage

Get medihaler ergotamine

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Frequently asked questions

What is the difference between D.H.E. 45 and Medihaler Ergotamine?

D.H.E. 45 contains Dihydroergotamine Mesylate, while Medihaler Ergotamine contains Ergotamine Tartrate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.