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CYMBALTA vs VIIBRYD

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 12, 2026·How we rate

Possible drug interaction. CYMBALTA and VIIBRYD are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

cymbaltaviibryd

Rating

New
72/100

Pharmacy pays

~$3.41 /30
~$29.59 /30

Type

RX
RX

Active ingredient

DULOXETINE HYDROCHLORIDE
VILAZODONE HYDROCHLORIDE

Manufacturer

Lilly
Abbvie

Dosage forms

Capsule, delayed release
Tablet

Drug class

Serotonin and Norepinephrine Reuptake Inhibitor
—

Boxed warning

None
Boxed warning

Half-life

about 12 hours (typically 8 to 17 hours)
—

Treats

Anxiety Disorders, Major Depressive Disorder, Diabetic Neuropathies
Major Depressive Disorder

Frequently asked questions

Which is cheaper, Cymbalta or Viibryd?

Cymbalta costs pharmacies less to acquire — about $3.41 vs $29.59 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Cymbalta and Viibryd?

Cymbalta contains Duloxetine Hydrochloride, while Viibryd contains Vilazodone Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.