CYCLOCORT vs PREDNISOLONE ACETATE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 9, 2026·How we rate

Possible drug interaction. CYCLOCORT and PREDNISOLONE ACETATE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CYCLOCORT	PREDNISOLONE ACETATE
Rating	72/100	58/100
Pharmacy pays	$4.90 /g	$0.60 /mL
Type	RX	RX
Active ingredient	AMCINONIDE	PREDNISOLONE ACETATE
Manufacturer	Astellas	Lupin
Dosage forms	Topical	Drops
Drug class	Corticosteroid	Corticosteroid
Boxed warning	None	None
Half-life	—	2 to 4 hours
Treats	Dermatitis, Facial Dermatoses, Foot Dermatoses	Adrenal Insufficiency, Hemolytic Anemia, Asthma

cyclocort prednisolone acetate

Rating

72/100

58/100

Pharmacy pays

$4.90 /g

$0.60 /mL

Type

Active ingredient

AMCINONIDE

PREDNISOLONE ACETATE

Manufacturer

Astellas

Lupin

Dosage forms

Topical

Drops

Drug class

Corticosteroid

Boxed warning

None

Half-life

—

2 to 4 hours

Treats

Dermatitis, Facial Dermatoses, Foot Dermatoses

Adrenal Insufficiency, Hemolytic Anemia, Asthma

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Frequently asked questions

Which is better-rated, Cyclocort or Prednisolone Acetate?

By our independent rating, Cyclocort scores higher — 3.6 vs 2.9 out of 5 for Prednisolone Acetate. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Cyclocort and Prednisolone Acetate?

Cyclocort contains Amcinonide, while Prednisolone Acetate contains Prednisolone Acetate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.