CYCLOCORT vs LOCOID LIPOCREAM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. CYCLOCORT and LOCOID LIPOCREAM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CYCLOCORT	LOCOID LIPOCREAM
Rating	72/100	New
Pharmacy pays	$4.91 /g	—
Type	RX	RX
Active ingredient	AMCINONIDE	HYDROCORTISONE BUTYRATE
Manufacturer	Astellas	Precision Dermat
Dosage forms	Topical	Topical
Drug class	Corticosteroid	Corticosteroid
Boxed warning	None	None
Half-life	—	about 1.5 hours
Treats	Dermatitis, Facial Dermatoses, Foot Dermatoses	Adrenal Insufficiency, Congenital Adrenal Hyperplasia, Ulcerative Colitis

cyclocort locoid lipocream

Rating

72/100

New

Pharmacy pays

$4.91 /g

—

Type

Active ingredient

AMCINONIDE

HYDROCORTISONE BUTYRATE

Manufacturer

Astellas

Precision Dermat

Dosage forms

Topical

Drug class

Corticosteroid

Boxed warning

None

Half-life

—

about 1.5 hours

Treats

Dermatitis, Facial Dermatoses, Foot Dermatoses

Adrenal Insufficiency, Congenital Adrenal Hyperplasia, Ulcerative Colitis

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Frequently asked questions

What is the difference between Cyclocort and Locoid Lipocream?

Cyclocort contains Amcinonide, while Locoid Lipocream contains Hydrocortisone Butyrate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.