CYCLOCORT vs HYDELTRASOL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. CYCLOCORT and HYDELTRASOL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CYCLOCORT	HYDELTRASOL
Rating	72/100	70/100
Pharmacy pays	$4.91 /g	$0.60 /mL
Type	RX	RX
Active ingredient	AMCINONIDE	PREDNISOLONE SODIUM PHOSPHATE
Manufacturer	Astellas	Merck
Dosage forms	Topical	Topical, Injectable
Drug class	Corticosteroid	Corticosteroid
Boxed warning	None	None
Half-life	—	2 to 4 hours
Treats	Dermatitis, Facial Dermatoses, Foot Dermatoses	Adrenal Insufficiency, Hemolytic Anemia, Asthma

cyclocort hydeltrasol

Rating

72/100

70/100

Pharmacy pays

$4.91 /g

$0.60 /mL

Type

Active ingredient

AMCINONIDE

PREDNISOLONE SODIUM PHOSPHATE

Manufacturer

Astellas

Merck

Dosage forms

Topical

Topical, Injectable

Drug class

Corticosteroid

Boxed warning

None

Half-life

—

2 to 4 hours

Treats

Dermatitis, Facial Dermatoses, Foot Dermatoses

Adrenal Insufficiency, Hemolytic Anemia, Asthma

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Frequently asked questions

Which is better-rated, Cyclocort or Hydeltrasol?

By our independent rating, Cyclocort scores higher — 3.6 vs 3.5 out of 5 for Hydeltrasol. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Cyclocort and Hydeltrasol?

Cyclocort contains Amcinonide, while Hydeltrasol contains Prednisolone Sodium Phosphate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.