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CYCLOCORT vs DESONATE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. CYCLOCORT and DESONATE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

72/100
New

Pharmacy pays

$4.91 /g
$0.28 /g

Type

RX
RX

Active ingredient

AMCINONIDE
DESONIDE

Dosage forms

Topical
Topical

Drug class

Corticosteroid
Corticosteroid

Boxed warning

None
None

Treats

Dermatitis, Facial Dermatoses, Foot Dermatoses
Facial Dermatoses, Foot Dermatoses, Hand Dermatoses

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Frequently asked questions

Which is cheaper, Cyclocort or Desonate?

Desonate costs pharmacies less to acquire — about $0.28 vs $4.91 per gm, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Cyclocort and Desonate?

Cyclocort contains Amcinonide, while Desonate contains Desonide — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.