CUPRIMINE vs XARTEMIS XR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 6, 2026·How we rate

Possible drug interaction. CUPRIMINE and XARTEMIS XR are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CUPRIMINE	XARTEMIS XR
Rating	74/100	72/100
Pharmacy pays	—	$0.03 /mL
Type	RX	RX
Active ingredient	PENICILLAMINE	ACETAMINOPHEN AND OXYCODONE HYDROCHLORIDE
Manufacturer	Valeant Pharm Intl	Mallinckrodt
Dosage forms	Capsule	Tablet, extended release
Drug class	Antirheumatic Agent	—
Boxed warning	Boxed warning	None
Half-life	—	about 3.5 to 4 hours
Treats	Rheumatoid Arthritis, Cystinuria, Hepatolenticular Degeneration	—

cuprimine xartemis xr

Rating

74/100

72/100

Pharmacy pays

—

$0.03 /mL

Type

Active ingredient

PENICILLAMINE

ACETAMINOPHEN AND OXYCODONE HYDROCHLORIDE

Manufacturer

Valeant Pharm Intl

Mallinckrodt

Dosage forms

Capsule

Tablet, extended release

Drug class

Antirheumatic Agent

—

Boxed warning

None

Half-life

—

about 3.5 to 4 hours

Treats

Rheumatoid Arthritis, Cystinuria, Hepatolenticular Degeneration

—

Frequently asked questions

Which is better-rated, Cuprimine or Xartemis XR?

By our independent rating, Cuprimine scores higher — 3.7 vs 3.6 out of 5 for Xartemis XR. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Cuprimine and Xartemis XR?

Cuprimine contains Penicillamine, while Xartemis XR contains Acetaminophen and Oxycodone Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.